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Rac-GTP 小鼠单抗/active Rac 抗体文献较新推荐/现货

2025/8/8 6:41:35发布26次查看
gtp酶是gtp/gdp结合蛋白。被细胞表面受体(gpcr)后, 它能调节下游效应器的功能。它可以结合gtp、水解gtp,因此在的gtp结合状态和非的gdp结合状态之间切换。它具有内在的gtp酶活性,可将gtp水解为gdp,从而使g蛋白失活。我们精心筛选的小鼠单抗体能捕捉到与gtp结合的具有活性的gtp酶。它们已被用于通过*组织化学监测细胞和组织中 g 蛋白的活化和分布。
001. the scaffold rho protein arh8/ bp1 synchronizes rac and rho signaling to facilitate cell migration
mol biol cell. 2023  pmid:36598812
002. downregulation of cyri-b promotes migration, invasion and emt by activating the rac1-stat3 pathway in gastric cancer
exp cell res. 2022  pmid:36584745
003. loss of cell–cell adhesion triggers cell migration through rac1-dependent ros generation
life sci alliance. 2022  pmid:36446524
004. catalpol inhibits hepatic stellate cell activation by reducing the formation and changing the contents of hepatocyte-derived extracellular vesicles
j cell commun signal. 2022  pmid:36508052
005. cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine **ing
mol biol cell. 2022  pmid:35653297
006. inhibition of rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice
cell death discov. 2022  pmid:35031595
007. smooth muscle rac1 contributes to pulmonary hypertension
bjp. 2022  pmid:35064565
008. rac1 mediates cadherin-11 induced cellular pathogenic processes in aortic valve calcification
cardiovasc pathol. 2022  pmid:35074515
009. a portable controllable compressive stress device to monitor human breast cancer cell protrusions at single-cell resolution
j clin invest. 2022  pmid:35104805
010. hepatic ischemia-reperfusion injury in mice was alleviated by rac1 inhibition – more than just ros-inhibition
j clin transl hepatol. 2022  pmid:35233372
011. targeting the asmase/s1p pathway protects from sortilin-evoked vascular damage in hypertension
j neuroinflammation. 2022  pmid:35284404
012. planar cell polarity-dependent asymmetric organization of microtubules for polarized positioning of the basal body in node cells
development. 2022  pmid:35420656
013. time of day-dependent alteration of hippocampal rac1 activation regulates contextual fear memory in rats
front mol neurosci. 2022  pmid:35782392
014. transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic nmda receptor
front bioeng biotechnol. 2022  pmid:35831873
015. arhgef37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating cdc42
j exp clin cancer res. 2022  pmid:35869555
016. organoid-on-a-chip model of human arpkd reveals mechanosensing pathomechanisms for drug discovery
sci adv. 2022  pmid: 36129975
017. differential dysregulation of granule subsets in wash-deficient neutrophil leukocytes resulting in inflammation
nat commun. 2022  pmid: 36130971
018. the pro-fibrotic response to lens injury is signaled in a pi3k isoform-specific manner
biomolecules. 2022  pmid:36139020
019. anti-angptl3-fld monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage
cell death dis. 2022  pmid:36229446
020. critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis
j cell commun signal. 2022  pmid:36284029
021. pten protein phosphatase activity is not required for tumour suppression in the mouse prostate
biomolecules. 2022  pmid:36291720
022. dock4 is required for the maintenance of cochlear hair cells and hearing function
fundamental research. 2022
武汉费斯德生物科技有限公司是美国neweast biosciences在中国的办事处。neweast biosciences 在十二年前研发俩种*特的抗体。这俩种抗体仅仅识别活性的gtp酶或者突变的oncogene。 gtp酶涉及(1)响应细胞表面受体的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过gtp酶控制囊泡外壳组装。oncogene侧是诱发癌症的基因。
我公司将向你提供以下三种抗体或者试剂盒: (1) 仅识别 gtp酶的活性构型的产品, 它可以让你能够量化gtp酶在细胞中的活性和分布。(2) 识别突变 oncogene蛋白, 但不认识相应**型的抗体。 (3) 对 camp 和 cgmp 具有**亲和力(*乙酰化)elisa检测试剂盒。这些产品被将近一千篇**评议的文章所引用。
武汉费斯德生物科技有限公司专注于g蛋白活性抗体及试剂盒,非乙酰化camp和cgmp试剂,点突变抗体等
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