anti-dc-sign抗体生产厂家
catalog number : byk-2557r
quantity size : 0.1ml (1mg/ml,lyophilized or liquid.buffer=0.01m pbs,ph 7.4 with 10 mg/ml bsa and 0.1% sodium azide.reconstitute with 0.1ml sterile distilled water.)
background: dendritic cells (dcs) that control immune responses were recently found to capture and transport hiv from the mucosal area to remote lymph nodes, where dcs hand over hiv to cd4+ t lymphocytes. dcs also amplify the amount of virus and extend the duration of viral infectivity. multiple strains of hiv1, hiv2 and siv bind to dcs via dcsign. icam3 is the natural ligand for dc-sign. a dc-sign homologue (termed cd299, dc-signr, l-sign and dcsign2) was identified recently. dc-sign forms a novel gene family with dc-signr and many alternatively spliced isoforms of dc-sign and dc-signr. the expression of dc-sign was found in mucosal tissues including placenta, small intestine, and rectum.
specificity :
anti-dc-sign is a rabbit polyclonal antibody unconjugated specific for dc-sign of human,mouse,ratuse for western blotting,elisa,immunoprecipitation and immunohistochemistryprotein g affinity chromatography purification, purity :>95%isotype: iggmol wt: 45kda
application :
western blotting=1:100-500 immunohistocry 1:100-500 elisa= 1:500-1000ihc-p=1:100-500ihc-f=1:100-500optimal working dilutions must be determined by the end user.
storage: store at -20℃ for one year. avoid repeated freeze/thaw cycles. the lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. when reconstituted in sterile ph 7.4 0.01m pbs or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
important note: this product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.