- 产品等级:医药级
nanohydroxyapatite
apperance partical size (nm) purity(%) usage
needle-like 60nm 96% food,toothpaste
needle-like 40nm 96% general,proteinisolate
needle-like 20nm 97.5% artificial bone
needle-like 20nm(w),150nm(l) 99% artificial bone (high pure)
short clavite 30nm(w),100nm(l) 99% artificialbone,artificial joint
fibrous 10nm(w),500nm(l) 99% artificial bone,artificial joint
globular 12μm 99% artificialbonecoating
needle-like 12μm 96% food,toothpaste
detaileddescription:
thetheoreticalcomposition of hydroxyapatite is ca10 (po4) 6 (oh) 2,ca / p of1.67, but due to the processes of preparation, the realcompositionis quite complex. ha is hexagonal crystal, is l6pcsymmetric and p63/ m space group, its structure is a hexagonalprism, with the c axisperpendicular to the plane is a hexagon, a,b-axis angle of 120o;,its lattice parameters is a = 9.43 ~ 9.38å;,c = 6.88 ~ 6.86å;, z =2, unit cell contains 10 ca2+,6xpo43-and 2 of oh-. ha surfacehas a surface of several possiblestates: (1) when a crystallinesurface oh, oh with 2 ca (ⅱ) ion isconnected, when the ha inaqueous solution, the position of thissurface at least in a momentoh vacancy , by two ca (ⅱ) ion with apositive charge, forming asuction position, this position can beadsorbed po43-or phosphategroups on the macromolecule or acarboxyl group. (2) when the caions in the surface of the crystal,since ca (ⅰ) and 6 chargednegatively charged o atom, when the hain aqueous solution, thesurface of ca (ⅰ) position vacancies in amoment, in ca (ⅰ) positionto form a strong adsorption sites, canabsorb sr3 +, k + and othercations and the group of proteinmolecules, and in the ca (ⅱ)position is the formation of a weakeradsorption sites. (3) po43-incrystal surface, h2o through hydrogenbonding withpo43-ions.
mainapplication:
1.afterhydroxyapatiteimplanted into the bone, because of its good affinityto the bonetissue, can induce undifferentiated mesenchymal cellstodifferentiate into bone cells, which is directly attached tothesurface of hydroxyapatite
2. from the chemical composition, it composed of calciumandphosphate, these two components are the most common constituentofbone tissue and bone tissue is a crystalline calciumhydroxyapatiteand phosphate amorphous form, thus hydroxyapatitestone bonesubstitute material, not only in composition, but also inthestructure of human bone tissue is consistent with calcium, itcanbe used for artificial joint to replace the bone
3.the bio-ceramic materials clinical application:artificialjoint,bone substitute, toothpaste, food andotherapplications.
上海泰康纳米化学科技有限公司
蒋先生
13618306260
上海市浦东新区