中文名称：二棕榈酰磷脂酰乙醇胺-聚乙二醇-叶酸；磷脂peg叶酸
化 学 名：1,2-distearoyl-sn-glycero-3-phosphoethanolamine-n-[folate(polyethyleneglycol)]
产品外观：淡黄色粉末
溶 解 度：>5mg/ml in hot water, chloroform, dmso
peg分子量：2000
整体分子量：3200
结 构 式：
产品纯度：90%
产品包装：100mg
价 格：2800元
保存条件：-20℃
保存时间：1年
产品用途：用于肿瘤主动靶向
产品描述：
dspe-peg-folate (dspe-peg-fol) conjugate,which can be incorporated into liposomes as a targeting ligand. folatereceptors are cellular surface markers for numerous solid tumors and myeloidleukemias.
folate targeted drug delivery has emergedas an alternative therapy for the treatment and imaging of many cancers andinflammatory diseases. due to its small molecular size and high bindingaffinity for cell surface folate receptors (fr), folate conjugates have theability to deliver a variety of molecular complexes to pathologic cells withoutcausing harm to normal tissues. complexes that have been successfully deliveredto fr expressing cells, to date, include protein toxins, immune stimulants,chemotherapeutic agents, liposomes, nanoparticles, and imaging agents. thisreview will summarize the applications of folic acid as a targeting ligand andhighlight the various methods being developed for delivery of therapeutic andimaging agents to fr-expressing cells.
供应商：西安凯新生物科技有限公司
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